Analysis of Interactions of NHC Type Molecules and NHC-Ag Complexes with VEGFR-2 and DNA: A Molecular Docking Study

Molecular docking is an important tool in drug research. Thanks to these calculations, the type and magnitude of interactions molecules with target are evaluated. It also possible perform more detailed analyzes than known experimental methods easy economical way by using results obtained current scientific developments examine different depending on bioactivity type. Cancer researches show that vascular endothelial growth factor effective proliferation cancer cells. Inhibition receptor regulates release this may be efficient method for designing anticancer agent. One receptors VEGFR-2. This can used as a molecule In addition, interaction DNA terms getting insight future studies. study, 1-allyl-3-benzylbenzimidazolium, 1-allyl-3-(naphthylmethyl)benzimidazolium, 1-allyl-3-(anthracen-9-yl-methyl)benzimidazolium,chloro[1-allyl-3-benzylbenzimidazolium-2-ylidene]silver(I), chloro[1-allyl-3-(naphthylmethyl)benzimidazolium-2-ylidene]silver(I), chloro[1-allyl-3-(anthracen-9-yl-methyl)benzimidazolium-2-ylidene]silver(I) VEGFR-2 were analyzed molecular methods.